The Chiefs opened as 3-point favorites Monday morning on most sports betting websites after their AFC Championship game victory on Sunday over the Buffalo Bills.
Brady's Buccaneers beat the Green Bay Packers on Sunday in the NFC Championship game to advance to the title game.
"We've had a few tough games in a row and the next game will be really tough, too," Brady told reporters on Sunday.
"We know what we're playing for and we've got two weeks to prepare. It's going to be a great opponent. It will be a really exciting couple of weeks for us."
The Buccaneers will become the first team in NFL history to play in a Super Bowl on their home field when they battle the Chiefs at 6:30 p.m. EST on Feb. 7 at Raymond James Stadium in Tampa, Fla.
The Chiefs beat the Buccaneers 27-24 in a regular-season matchup on Nov. 29 in Tampa. Brady threw three touchdown passes and two interceptions while Patrick Mahomes threw three touchdown passes and no interceptions in that game.