If you don't have a top quarterback option, take a look at my weekly waiver wire article. There are several capable gunslingers with great matchups who should be on your streaming radar.
You also should remove Denver Broncos, Houston Texans, Jacksonville Jaguars, New England Patriots, Philadelphia Eagles and Washington Redskins players from your lineup, as those teams have Week 10 byes.
Here are some of my favorite players in this week's top 20 quarterback rankings:
Drew Brees hasn't missed a beat since returning from his thumb injury. The New Orleans Saints star threw for 373 yards and three scores in Week 8. He is my No. 1 quarterback for Week 10. Brees and the Saints are facing the Atlanta Falcons, a team allowing the third-most fantasy points per game. Brees should post at least 300 passing yards and have at least two passing scores in this matchup.
Arizona Cardinals rookie Kyler Murray is my No. 2 quarterback for Week 10. Murray has a matchup against the Tampa Bay Buccaneers, a team allowing the fourth-most fantasy points per game to quarterbacks. Murray's rushing totals have been modest lately, but I'm expecting a strong showing on the ground and at least 250 passing yards from the rookie in this plus matchup. Start Murray with confidence.
Los Angeles Rams quarterback Jared Goff is my No. 8 option this week. Goff has thrown multiple touchdown passes in back-to-back games entering his Week 10 matchup against the Pittsburgh Steelers. The Steelers have been stingy about giving up fantasy points to quarterbacks, but I see the Rams dominating this game. Goff is a starter in Week 10, regardless of league size.
Brian Hoyer is a great bye week fill in option if starting quarterback Jacoby Brissett misses the Indianapolis Colts' Week 10 matchup against the Miami Dolphins. The Dolphins are allowing the sixth-most fantasy points per game to quarterbacks. I have Hoyer listed as my No. 13 option, based on the assumption that Brissett misses this game due to his knee injury.
Tennessee Titans quarterback Ryan Tannehill is playing great from a fantasy football perspective. I have him as my No. 14 quarterback for Week 10, making him a great bye week play if your normal starter is out. The Titans are facing the Kansas City Chiefs, a unit allowing the 10th-most fantasy points per game to quarterbacks. Tannehill thew multiple touchdown passes in back-to-back games entering his Week 9 showing. He passed for a season-high 331 yards while throwing a touchdown pass and picking up a rushing score last week against the Carolina Panthers. I'm expecting multiple touchdown passes from Tannehill in this spot.
Week 10 fantasy football quarterback rankings
1. Drew Brees, New Orleans Saints vs. ATL
2. Kyler Murray, Arizona Cardinals at TB
3. Lamar Jackson, Baltimore Ravens at CIN
4. Aaron Rodgers, Green Bay Packers vs. CAR
5. Jameis Winston, Tampa Bay Buccaneers vs. ARI
6. Russell Wilson, Seattle Seahawks at SF
7. Dak Prescott, Dallas Cowboys vs. MIN
8. Jared Goff, Los Angeles Rams at PIT
9. Matt Ryan, Atlanta Falcons at NO
10. Daniel Jones, New York Giants at NYJ
13. Brian Hoyer, Indianapolis Colts vs. MIA
14. Ryan Tannehill, Tennessee Titans vs. KC
16. Matt Moore, Kansas City Chiefs at TEN
18. Ryan Fitzpatrick, Miami Dolphins at IND
19. Mason Rudolph, Pittsburgh Steelers vs. LAR
20. Kyle Allen, Carolina Panthers at GB