The Lions' training staff covered Kearse's lower leg with a towel before applying an air cast, according to The Athletic. He was carted off the field with his left leg heavily wrapped.
The 29-year-old wideout's injury occurred while blocking for Lions running back Ty Johnson. Patriots safety Terrence Brooks attempted to tackle the tailback but crashed into the back of Kearse's lower left leg.
Kearse is expected to miss the entire 2019-20 campaign due to the injury, according to NFL Media.
Kearse signed a one-year contract with the Lions this off-season. He has 255 receptions for 3,290 yards and 17 touchdowns in 99 career NFL games.