A source told NFL Network on Wednesday that the signing is pending a physical. The six-year veteran was a fourth round pick by the Falcons in the 2013 NFL Draft. Toilolo, 27, signed with the Lions last off-season.
He had 263 yards and a score on 21 receptions in 16 games during his 2018 campaign. The 6-foot-8, 268-pound pass-catcher has 986 yards and eight scores on 95 receptions in 95 career appearances.
Toilolo will provide veteran depth behind 49ers star tight end George Kittle. The 49ers also have tight ends Garrett Celek and Kaden Smith on the roster. Smith was a sixth-round pick by the 49ers in the 2019 NFL Draft.
Kittle, 25, made his first Pro Bowl in 2018 after hauling in a career-high 88 receptions for 1,377 yards and five touchdowns in 16 starts for the 49ers. He led all tight ends in receiving yards last season.