Giants coach Pat Shurmur officially ruled Beckham out when he met with reporters on Friday. Beckham finishes his 2018 campaign with 1,052 yards and six touchdowns on 77 receptions in 12 games. The three-time Pro Bowl selection has played in a total of 16 games in the last two seasons combined due to multiple injuries.
Beckham is dealing with a quadriceps injury. The Giants also ruled out Mario Edwards, Alec Ogletree, Rhett Ellison and Russell Shepard for Sunday's NFC East clash.
"We were right there so many games but just couldn't get over the hump ... this season definitely didn't go the way we wanted but you take it as a learning lesson," Beckham told reporters Friday.
Beckham pulled in three catches for 35 yards and a score -- while being targeted nine times -- in his last game, a 30-27 win on Dec. 2 against the Chicago Bears. He suffered the quad injury in a practice the following week.
The Giants and Cowboys kickoff at 1 p.m. on Sunday at MetLife Stadium in East Rutherford, N.J.