Diggs, who had been limited in practice Thursday and Friday due to a knee injury, will be good to go for Monday night's matchup against the Seattle Seahawks.
The Vikings (6-5-1) are holding down the sixth and final playoff spot in the NFC, one-half game ahead of Carolina, Philadelphia and Washington and a half-game behind Seattle (7-5).
Diggs already has matched his career high with 84 receptions despite sitting out a win over Detroit on Nov. 4. He also has 839 yards and six touchdowns.
A fifth-round pick of the Vikings in the 2015 NFL Draft, Diggs had five receptions for 49 yards in last weekend's 24-10 loss at New England. He had scored in each of his previous three games while amassing 31 receptions for 322 yards.
Diggs and Adam Thielen form one of the most lethal wideout tandems in the league, helping Minnesota's passing game rank seventh in the NFL with an average of 274.8 yards.
Last season, Diggs established a career high with eight touchdown catches on 64 receptions for 89 yards.
For his career, Diggs has 284 catches for 3,311 yards and 21 touchdowns in 51 games.