Green, who was not listed on the team's injury report Friday, will provide a much-needed boost for the slumping Bengals after he sat out the past three games due to a toe injury.
Cincinnati (5-6) lost all three games without Green in the lineup to drop into ninth place in the crowded AFC race for the sixth and final playoff slot -- one game behind the division rival Baltimore Ravens.
The return of Green comes at an optimum time for the Bengals. Starting quarterback Andy Dalton suffered a season-ending thumb injury in Sunday's loss to Cleveland and underwent surgery on Tuesday.
Backup Jeff Driskel, who replaced Dalton against the Browns, will make his first career start against the Broncos, who are among four AFC teams with 5-6 records.
A seven-time Pro Bowl selection, Green suffered the injury in a 37-34 win over the Tampa Bay Buccaneers on Oct. 28.
The 30-year-old Green has 45 receptions for 687 yards and a team-leading six touchdown catches for the Bengals.
Green has eclipsed 100 yards receiving in a franchise-best 32 games in his career. He has 601 receptions for 8,900 yards and 63 touchdowns in 110 contests since being selected by Cincinnati with the No. 4 overall pick in the 2011 NFL Draft.