Although Diggs was among five players listed as questionable by the Vikings, his chances to play Sunday appeared to dim when the team signed wide receiver Chad Beebe from the practice squad on Saturday.
Diggs was unable to practice all week due to a rib injury suffered in last weekend's 30-20 loss to the New Orleans Saints.
The fourth-year wideout is having a strong season for Minnesota with 58 receptions for 587 yards and four touchdowns.
Diggs had 10 receptions for 119 yards and a score in the loss to the Saints. It marked the third time this season that he has had at least 100 yards or 10 catches in a game.
Beebe has never played in an NFL game. The former undrafted free agent out of Northern Illinois is the son of former Buffalo Bills wideout Don Beebe. He had nine catches for 95 yards and a pair of touchdowns during the preseason. To clear a roster spot for Beebe, the Vikings waived tackle Storm Norton.
Diggs, who teams with Adam Thielen to form one of the best wideout tandems in the league, is on pace to set career highs across the board. He had 64 catches for 849 yards and a personal-best eight touchdowns last season.
A fifth-round pick out of Maryland in the 2015 NFL Draft, Diggs had a career-best 84 receptions for 903 yards and four scores in 2016.
Minnesota takes a 4-3-1 record into Sunday's matchup versus Detroit (3-4).