Stafford threw more passes in Friday's practice after throwing none on Wednesday and only light tosses on Thursday.
Detroit coach Jim Caldwell noted the progression while meeting with reporters on Friday.
Stafford has started 108 consecutive games, the third-longest current streak among NFL quarterbacks. Regardless, backup Jake Rudock received a large dose of practice repetitions this week.
Meanwhile, right tackle Rick Wagner was ruled out of the contest with an ankle injury. Wagner suffered the injury when Stafford fell on him during last Sunday's game against the Baltimore Ravens.
Stafford is one of 10 Lions listed as questionable. The others are running back Ameer Abdullah (neck), cornerback Jamal Agnew (knee), defensive ends Ezekiel Ansah (ankle) and Cornelius Washington (shoulder), offensive tackles Emmett Cleary (ankle) and Corey Robinson (foot), guard T.J. Lang (foot), punter Sam Martin (right foot) and center Travis Swanson (knee).