Wright, who signed a one-year deal with Chicago in the offseason, caught three passes for 35 yards on the drive, helping to set up a 1-yard touchdown pass to Dion Sims, giving the Bears a 7-0 lead.
Chicago then added points through special teams, when after forcing a Titans punt, Roy Robertson-Harris broke through the middle of the line, blocking Brett Kern's punt. The Bears recovered but it was out of the end zone, resulting in a safety and a 9-0 lead.
The Titans' only scoring chance of the first half went by the boards, when Ryan Succop missed a 40-yard field goal wide left with 3:14 to play.
Glennon later directed another scoring drive for Chicago, taking the Bears 47 yards in 10 plays and getting a 41-yard field goal from Connor Barth that pushed the lead to 12-0.
The Titans left their starting offense on the field for two second-half drives, and finally got points on the first play of the fourth quarter when running back Derrick Henry scored from 3 yards out on what was ruled a touchdown pass from Marcus Mariota, who finished 12 of 21 for 193 yards and one score.
Bears wide receiver Tanner Gentry caught a 45-yard touchdown from rookie Mitchell Trubisky in the fourth quarter.
Chicago improved to 2-1 overall in the preseason and will close out the preseason Thursday night against the Cleveland Browns.
The Titans dropped to 1-2 and close out the preseason at Kansas City on Thursday night.