Cobb, who was listed as questionable on Friday's injury report, missed the last two games with an ankle injury. He was a limited participant in practice this past week.
Packers fullback Aaron Ripkowski was active after being added to the injury report on Saturday with a shoulder injury. Ripkowski led the Packers in rushing last week against the Detroit Lions with 61 yards.
Cornerback Damarious Randall also was active for the Packers after being listed as questionable with a knee injury.
For the Giants, defensive end Owa Odighizuwa was inactive as expected after being listed as doubtful with a hamstring injury.
Giants rookie tight end Jerell Adams, who has been the team's No. 2 tight end for the second half of the season, was a surprise inactive. Adams missed the regular-season finale last Sunday with a shoulder injury. He was not listed on Friday's injury report.