Casey said the team wants to avoid stress on Griffin's body in the second of a back-to-back game.
It will be just the third time this season that Griffin that will not play in a game, the other two also coming on the back end of a back-to-back affair.
The forward scored 25 points and had eight rebounds in the Pistons' 110-107 victory Sunday over the Toronto Raptors.
It was a return to form for Griffin, who was slowing down during a three-game stretch before the effort against Toronto, averaging 12.7 points per game.
This season, the 30-year-old is averaging 24.7 points and 7.6 rebounds per game for Detroit, which enters play Monday at 36-33, good for sixth in the NBA's Eastern Conference.