Durant, will undergo an MRI, the Warriors announced. He suffered the injury 57 seconds into the game. Warriors big man ZaZa Pachulia, fouled on the play by Washington's Marcin Gortat, fell backwards into the legs of Durant, who was standing in the left corner.
The 2014 Most Valuable Player showed discomfort and Golden State coach Steve Kerr called for a timeout with 10:26 left in the period. Durant immediately left the court and headed toward the locker room.
Significant buzz existed for this game beyond the usual involving Golden State, which became the first NBA team this season with 50 wins following its victory over Philadelphia on Monday.
Durant grew up in the nearby Maryland suburbs. Tuesday's appearance was the first since the former Oklahoma City star signed with Golden State in free agency. He did so without giving the Wizards a meeting even though Washington geared much of its roster construction over the previous two seasons in the hopes of luring, as many fans dubbed the movement, "KD2DC."
Some fans greeted Durant with boos during the introductions and when he touched the ball.
Durant also suffered a hamstring injury in his lone appearance in Washington last season when he was with Oklahoma City.
Washington led 40-26 after the first quarter.