Love was kept out of Monday's practice to rest his knee.
"He is continuing treatments related to the contusion and will not travel to Milwaukee with the Cavs to play the Bucks tomorrow night in Milwaukee," the team said in a release.
Cavaliers coach Tyronn Lue also announced that Love would be questionable for the second half of Cleveland's home-and-home matchup against the Bucks at Quicken Loans Arena in Cleveland on Wednesday night.
"He took a blow to the knee, knee-to-knee, and it swelled up on him, and it's kind of stiff," Lue told reporters Monday.
Love is averaging 22.3 points and 10.7 rebounds in 24 games this season.