The team announced Monday that Ramos suffered a torn ACL and sprained MCL in Sunday's game against the Boston Red Sox. The veteran catcher will require season-ending surgery to repair the knee injury.
Ramos injured his knee during the seventh inning of Sunday's game against the Red Sox. He fielded a weak hit right in front of home plate and was throwing to second base when his left knee buckled, causing him to collapse on the infield grass.
The 34-year-old Ramos played in 44 games this season -- nine with the Indians and 35 with the Detroit Tigers. He had a .226 batting average with two home runs and seven RBIs for the Indians, who have been playing without Gold Glove catcher Roberto Perez for most of the season.
Perez was put on the injured list earlier this month due to right shoulder inflammation and back spasms. He spent 60 days on the IL earlier in the season after having surgery on his right middle finger, which he broke in April.
Austin Hedges has handled most of the Indians' catching duties this season in Perez's absence.
Ramos drove in two runs during Sunday's matchup against Boston. After Ramos was injured, Hedges replaced him in the game and bashed a game-tying home run.