The 48-degree temperatures may have been to blame for the uncharacteristic struggles of Verlander and Sale, as the teams battled their way to a sixth-inning tie. That all changed when Carlos Correa singled to give the Astros a lead they would never relent and their fifth straight victory in the postseason.
Josh Reddick added a solo shot to lead off the ninth and Yuli Gurriel blasted a three-run homer to put things way out of reach.
Game 2 is Sunday, again in Boston, with David Price set to take the mound for the Red Sox against the Astros' Gerrit Cole. Price is 0-9 in 10 postseason starts.