CHAPEL HILL, N.C. -- Lamar Jackson threw for three touchdowns and rushed for three more as No. 17 Louisville defeated North Carolina 47-35 on Saturday.
Jackson gained 132 yards on the ground and threw for 393 more for Louisville (2-0). His 526 yards of total offense marked the most ever allowed by North Carolina to one player.
The defending Heisman Trophy winner recorded his 15th game with at least 100 yards rushing, tying a school record. His 35 career rushing touchdowns are third on the Cardinals' all-time list.
Running back Malik Williams rushed for 149 yards on 13 carries as Louisville piled up 705 yards of total offense.
Brandon Harris completed 17 of 23 passes for 216 yards while Austin Proehl caught eight passes for 120 yards as North Carolina dropped to 0-2 for the first time since 2010.
No. 1 Alabama 41, Fresno State 10
TUSCALOOSA, Ala. -- Jalen Hurts rushed for a pair of touchdowns and 154 yards as top-ranked Alabama routed Fresno State.
Hurts recorded touchdown runs of 55 yards and three yards in the opening minutes of the first and second quarters as Alabama (2-0) totaled 305 yards on the ground. He also completed 14 of 18 passes for 128 yards.
Chason Virgil completed 21 of 34 passes for 180 yards for Fresno State (1-1).
No. 4 Penn State 33, Pittsburgh 14
STATE COLLEGE, Pa. -- Saquon Barkley racked up 183 all-purpose yards and scored two touchdowns on 20 touches for No. 4 Penn State.
Trace McSorley completed 15 of 28 passes for 164 yards, three touchdowns and an interception. Tight end Mike Gesicki caught two touchdown passes for the Nittany Lions (2-0), who avenged last season's loss to Pittsburgh (1-1).
Panthers quarterback Max Browne completed 19 of 32 passes for 138 yards. Under pressure for most of the afternoon, he was sacked five times and threw two interceptions.
No. 8 Michigan 36, Cincinnati 14
ANN ARBOR, Mich. -- Ty Issac rushed for 133 yards on 20 carries to help lead the Wolverines to a 36-14 win over the Bearcats in their home opener.
The Wolverines (2-0) also returned two interceptions for touchdowns. Tyree Kinnel had a 28-yard return in the first quarter and Lavert Hill had a 24-yard return late in the fourth quarter.
Quarterback Wilton Speight completed 17 of 29 passes for 221 yards while Hayden Moore finished 15 of 40 for 132 yards for Cincinnati (1-1).
No. 9 Wisconsin 31, Florida Atlantic 14
MADISON, Wis. -- Jonathan Taylor rushed for three touchdowns and 223 yards in his first career start as the Badgers cruised to a win.
Taylor had 26 carries in place of injured sophomore Bradrick Shaw. Quarterback Alex Hornibrook completed 16 of 28 passes for 201 yards for Wisconsin (2-0).
Florida Atlantic (0-2) quarterback Daniel Parr was finished 9 of 19 for 142 yards.
No. 18 Virginia Tech 27, Delaware 0
BLACKSBURG, Va. -- No. 18 Virginia Tech forced two turnovers and recorded four sacks in its rout of Delaware.
Virginia Tech (2-0) allowed 223 yards while also getting a punt return touchdown from Greg Stroman and two field goals from Joey Slye.
Hokies quarterback Josh Jackson passed for 222 yards and two touchdowns. Quarterback Joe Walker passed for 116 yards for Delaware (1-1).
No. 19 Kansas State 55, Charlotte 7
MANHATTAN, Kan. -- Safety Kendall Adams returned a pair of interceptions for touchdowns as the Wildcats breezed to a win.
Adams recorded interception returns of 30 and 46 yards as Kansas State (2-0) bolted to a 31-7 lead in the second quarter. The Wildcats have 109 non-offensive touchdowns since 1999, the most in the nation by any FBS team.
Kansas State quarterback Jesse Ertz was an efficient 16 of 21 for 178 yards. Charlotte (0-2) quarterback Hassan Klugh was 8 of 19 for 33 yards and scored the lone touchdown.
No. 23 TCU 28, Arkansas 7
FAYETTEVILLE, Ark. -- Darius Anderson and Sewo Olonilua ran for late touchdowns as No. 23 TCU improved to 2-0.
Anderson scored on a 14-yard TD with 2:18 remaining. Fourteen seconds later, after Arkansas (1-1) fumbled the kickoff, Olonilua ran in from 13 yards for his second touchdown.
TCU quarterback Kenny Hill completed 21 of 31 passes for 166 yards. Arkansas quarterback Austin Allen was 9 of 23 for 138 yards.
No. 25 Tennessee 42, Indiana State 7
KNOXVILLE, Tenn. -- Running back Ty Chandler returned the opening kickoff 91 yards for a touchdown and sophomore running back Carlin Fils-aime scored two touchdowns to lead No. 25 Tennessee.
Quarterback Quinten Dormady completed 13 of 18 passes with two touchdowns and an interception to help Tennessee improve to 2-0 and set up a showdown next week with No. 22 Florida.
Indiana State (0-2) quarterback Cade Sparks completed 8 of 17 for 70 yards, and running back Lemonte Booker rushed for 76 yards on 15 carries.