Nov. 10, 2012 / 3:58 PM

COL FB: Syracuse 45, Louisville 26

SYRACUSE, N.Y., Nov. 10 (UPI) -- Ryan Nassib threw three touchdown passes Saturday and Syracuse handed 10th-ranked Louisville its first loss of the season 45-26.

Nassib completed 15-of-23 passes for 246 yards for the Orange (5-5, 4-2 Big East) and Prince-Tyson Gulley ran for two scored to snap a three-game losing streak. Gulley ran for 98 yards and scored twice in the first half to give Syracuse a 31-13 lead at halftime.

Syracuse scored three touchdowns in the second quarter and limited the Cardinals (9-1, 4-1) to a field goal in the closing seconds of the period.

Jerome Smith ran for 144 yards and a touchdown for Louisville. Teddy Bridgewater completed 36-of-50 passes for 422 yards and three touchdowns for the Cardinals, who gained only 48 yards on the ground and committed two turnovers.

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