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Sept. 23, 2012 / 1:10 AM

COL FB: Florida State 49, Clemson 37

TALLAHASSEE, Fla., Sept. 23 (UPI) -- EJ Manuel amassed 380 passing yards and ran for another 103 yards Saturday in fourth-ranked Florida State's 49-37 win over No. 9 Clemson.

Manuel tossed for two touchdowns, completing 27-of-35 pass attempts, and carried the ball 12 times for Florida State (4-0, 2-0 ACC).

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Chris Thompson rushed for 103 and two TDs on 15 carries and James Wilder Jr. also scored twice for the Seminoles.

Clemson (3-1, 0-1) lost despite a three-touchdown performance from Tajh Boyd, who passed for 237 yards on 20-of-36 efficiency and also ran the ball 18 times for 44 yards.

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