Sept. 10 (UPI) -- The start of the 2021 NFL season, the U.S. Open tennis finals and a full slate of college football matchups top the weekend sports schedule. NASCAR's playoffs and MLB and international soccer games also air this weekend.
Tom Brady's Tampa Bay Buccaneers battled the Dallas Cowboys in the first game of the NFL season Thursday in Tampa, Fla. Fourteen additional games air Sunday. Week 1 ends when the Las Vegas Raiders host the Baltimore Ravens on Monday Night Football.
More than 125 games air from Friday through Sunday between college football and the NFL.
Week 1 NFL schedule
The first full slate of Sunday games for the 2021 NFL campaign features nine matchups at 1 p.m. EDT, four games at 4:25 p.m. and one game at 8:20 p.m.
Fox's 1 p.m. EDT Sunday schedule features: the Indianapolis Colts vs. the Seattle Seahawks; the Cincinnati Bengals vs. the Minnesota Vikings; the San Francisco 49ers vs. the Detroit Lions; and the Philadelphia Eagles vs. the Atlanta Falcons.
CBS's 1 p.m. EDT Sunday matchups include: The Jacksonville Jaguars vs. the Houston Texans; the Los Angeles Chargers vs. the Washington Football Team; the New York Jets vs. the Carolina Panthers; the Arizona Cardinals vs. the Tennessee Titans; and the Pittsburgh Steelers vs. the Buffalo Bills.
The Kansas City Chiefs host the Cleveland Browns at 4:25 p.m. EDT Sunday on CBS. The New England Patriots host the Miami Dolphins at 4:25 p.m. on CBS.
The New Orleans Saints host the Green Bay packers at 4:25 p.m. EDT Sunday on Fox. The New York Giants also host the Denver Broncos at 4:25 p.m. Sunday on Fox.
The Los Angeles Rams host the Chicago Bears in the first Sunday Night Football matchup of 2021. That game airs at 8:20 p.m. EDT on NBC and streams on Peacock.
Djokovic's calendar year Grand Slam
No. 1 Novak Djokovic of Serbia is just two wins from a calendar-year Grand Slam. His next match is against No. 4 Alexander Zverev of Germany.
Djokovic won the 2021 Australian Open for his first Grand Slam of his quest. He added titles at Wimbledon and French Open. Zverev denied Djokovic's chance at a Golden Slam, when he defeated the Serbian in the 2020 Summer Games singles semifinals.
Djokovic will attempt to avenge that loss in the second men's singles semifinal Friday night at the USTA Billie Jean King National Tennis Center in Forest Hills, N.Y.
No. 2 Daniil Medvedev of Russia faces No. 15 Felix Auger-Aliassime of Canada in the first semifinal at 3 p.m. EDT Friday at Arthur Ashe Stadium. Both matches air on ESPN.
The 2021 U.S. Open women's singles final airs at 4 p.m. EDT Saturday on ESPN. The winners of the Djokovic-Zverev and Medvedev-Auger-Aliassime matches face off in the men's singles final at 4 p.m. EDT Sunday on ESPN.
College football matchups
Week 2 of the 2021 college football campaign continues with four games Friday and 108 games Saturday.
Coastal Carolina, the No. 19 team in the Coaches Poll, hosts Kansas in the first game of the weekend at 7:30 p.m. EDT Friday on ESPN.
No. 1 Alabama hosts Mercer at 4 p.m. EDT Saturday on SEC Network. UAB battles No. 2 Georgia at 3:30 p.m. EDT Sunday on ESPN2.
No. 3 Ohio State hosts No. 11 Oregon in one of the best matchups of the weekend. That game kicks off at noon EDT Saturday on Fox. No. 5 Texas A&M battles Colorado at 3:30 p.m. Saturday on Fox.
No. 10 Iowa State hosts No. 12 Iowa in another matchup between ranked teams at 4:30 p.m. EDT Saturday on ABC.
Friday
MLB
Giants at Cubs at 2:20 p.m. EDT on MLB Network (Out of market only)
Yankees at Mets at 7:10 p.m. EDT on MLB Network (Out of market only)
Tennis
U.S. Open: Felix Auger-Aliassime vs. Daniil Medvedev in men's semifinal at 3 p.m. EDT on ESPN
U.S. Open: Novak Djokovic vs. Alexander Zverev in men's semifinal after first match on ESPN
Soccer
MLS: Orlando at Atlanta at 7 p.m. EDT on ESPN+
MLS: Portland at Vancouver at 10 p.m. EDT on ESPN+
College football
Kansas at North Carolina at 7:30 p.m. EDT on ESPN2
UTEP at Boise State at 9:30 p.m. EDT on FS1
Saturday
Soccer
Premier League: Tottenham Hotspur at Crystal Palace at 7:30 a.m. EDT on NBCSN
Bundesliga: Dortmund at Bayer Leverkusen at 9:30 p.m. EDT on ESPN+
Premier League: Manchester City at Leicester City at 10 a.m. EDT on Peacock Premium
Premier League: Newcastle United at Manchester United at 10 a.m. EDT on USA
Ligue 1: Clermont Foot at PSG at 11 a.m. EDT on beIN Sports
Serie A: Juventus at Napoli at noon EDT on beIN Sports
Bundesliga: Bayern Munich at RB Leipzig at 12:30 p.m. EDT on espn+
Premier League: Aston Villa at Chelsea at 12:30 p.m. EDT on NBC
MLS: Los Angeles Galaxy at Colorado at 3:30 p.m. EDT on ESPN+
MLS: Minnesota at Seattle at 5 p.m. EDT on ESPN+
MLS: NYCFC at New England at 7 p.m. EDT on ESPN+
MLS: DC United at New York Red Bulls at 7 p.m. EDT on ESPN+
MLS: Nashville at Montreal at 8 p.m. EDT on ESPN+
MLS: Toronto at Cincinnati at 8 p.m. EDT on ESPN+
MLS: Columbus at Miami at 8 p.m. EDT on ESPN+
MLS: San Jose at Dallas at 8:30 p.m. EDT on ESPN+
MLS: Austin at Houston at 8:30 p.m. EDT on ESPN+
MLS: Chicago at Kansas City at 8:30 p.m. EDT on ESPN+
College football
Alabama State at Auburn at noon EDT on SEC Network
South Carolina at East Carolina at noon EDT on ESPN2
Pittsburgh at Tennessee at noon EDT on ESPN
Oregon at Ohio State at noon EDT on Fox
Tulsa at Oklahoma State at noon EDT on FS1
Florida at South Florida at 1 p.m. EDT on ABC
Middle Tennessee at Virginia Tech at 2 p.m. EDT on ACC Network Extra
Toledo at Notre Dame at 2:30 p.m. EDT on Peacock
UAB at Georgia at 3:30 p.m. EDT on ESPN2
Texas A&M vs. Colorado at 3:30 p.m. EDT on Fox
Ball State at Penn State at 3:30 p.m. EDT on FS1
Murray State at Cincinnati at 3:30 p.m. EDT on ESPN+
Air Force at Navy at 3:30 p.m. EDT on CBS
Mercer at Alabama at 4 p.m. EDT on SEC Network
Iowa at Iowa State at 4:30 p.m. EDT on ABC
South Carolina State at Clemson at 5 p.m. EDT on ACC Network
Western Carolina at Oklahoma at 7 p.m. EDT on Pay Per View
Texas at Arkansas at 7 p.m. EDT on ESPN
NC State at Mississippi State at 7 p.m. EDT on ESPN2
Appalachian State at Miami at 7 p.m. EDT on ESPNU
Eastern Michigan at Wisconsin at 7 p.m. EDT on fS1
Austin Peay at Ole Miss at 7:30 p.m. EDT on ESPN+
Georgia State at North Carolina at 7:30 p.m. EDT on ESPN3
Washington at Michigan at 8 p.m. EDT on ABC
Utah at BYU at 10:15 p.m. EDT on ESPN
Stanford at USC at 10:30 p.m. EDT on Fox
UNLV at Arizona State at 10:30 p.m. EDT on ESPN2
Hawaii at Oregon State at 11 p.m. EDT on FS1
MLB
Giants at Cubs at 2:20 p.m. EDT on MLB Network (Out of market only)
Yankees at Mets at 7:40 p.m. EDT on Fox
NASCAR
Xfinity Series Go Bowling 250 at 2:30 p.m. EDT on NBCSN
Cup Series Federated Auto Parts 400 Salute to First Responders at 7:30 p.m. EDT on NBCSN
Tennis
U.S. Open: Women's final at 4 p.m. EDT on ESPN
Sunday
Soccer
La Liga: Atletico Madrid at Espanyol at 8 a.m. EDT on ESPN+
Premier League: Liverpool at Leeds United at 11:30 a.m. EDT on NBCSN
La Liga: Celta Vigo at Real Madrid at 3 p.m. EDT on ESPN+
MLS: Salt Lake City at LAFC at 10:30 p.m. EDT on ESPN+
MLB
Red Sox at White Sox at 2:10 p.m. EDT on TBS (Out of market only)
Yankees at Mets at 8:08 p.m. EDT on ESPN
Tennis
U.S. Open: Men's final at 4 p.m. EDT on ESPN