Murray announced Friday on social media that he accepted a wild card for the singles draw in the tournament. The first round of the event starts Monday.
The 32-year-old has been participating in doubles matches since undergoing hip-resurfacing surgery after losing in the first round at the Australian Open in January. The former world No. 1 hinted at retirement but returned in June at Queen's Club and won the doubles trophy with Feliciano Lopez.
Murray paired up with Pierre-Hugues Herbert in the men's doubles draw at Wimbledon. He then partnered with Serena Williams at the All England Club.
The Western & Southern Open and the Winston-Salem Open are the last two tournaments before the season's final major. The U.S. Open begins Aug. 26 in New York City.