Cornerback Darius Butler immediately clutched his right hamstring after intercepting Trevor Siemian in the flat. Butler, who had plenty of open field in front of him, was ruled out for the rest of the game by the team.
Wide receiver Donte Moncrief exited in the first quarter with what the team said was a head and neck injury. The Colts said Moncrief was questionable to return.
Defensive tackle Hassan Ridgeway also left the game to be evaluated for a concussion. Ridgeway was cleared to return after passing the NFL's concussion protocol and Cromartie was back on the field for the Colts in the second quarter.
For the Broncos, tackle Donald Stephenson was sidelined in the first quarter with a calf injury. The team said he was questionable to return.
The Colts came into the game without cornerbacks Vontae Davis (ankle) and Patrick Robinson (concussion) as well as safety T.J. Green (knee). Outside linebacker Trent Cole did not make the trip to Denver because of a back injury.