The move is retroactive to May 10.
Brantley, 28, begins his second trip on the disabled list in 2016 after beginning the season rehabbing his right shoulder following offseason surgery in November to repair a torn labrum. He has appeared in 11 games, batting .231 (9-for-39) with seven RBIs.
Last season, Brantley hit .310 with 15 homers, a league-leading 45 doubles and 84 RBIs in 137 games.
To fill the roster spot, the Indians called up utility player Michael Martinez from Triple-A Columbus and moved catcher Roberto Perez (thumb surgery) to the 60-day DL.
Martinez, 33, has batted .288 with two home runs and 12 RBIs in 27 games at Columbus. Defensively he has appeared in 14 games at second base, six games at shortstop, five games in center field and one game at third base.