According to the Charlotte Observer, Richardson last missed the league meetings in 2009 after undergoing heart transplant surgery.
Team president Danny Morrison will represent the Panthers for the three-day meetings starting Monday in Boca Raton.
Richardson, who will turn 80 in July, was in New York last week for a retirement party for a league official, according to the newspaper.
This week's meetings are the first league-wide gathering since owners voted in January to allow the St. Louis Rams to move to Los Angeles.
Richardson, a member of the league's L.A. committee, emerged in January on the short end of the Los Angeles vote, with his preferred alternative of the San Diego Chargers and Oakland Raiders moving to Carson, Calif., being soundly defeated.
Owners voted 30-2 in favor of moving the Rams to Inglewood, and Richardson was not pleased with the decision at the time.
"I think it took a little steam out of him for a while," Giants owner John Mara told the Charlotte Observer in January. "He spent an enormous amount of time on that committee."