Brandon Saad put the Blackhawks ahead for good in the third period and his teammates held off a frantic late push from the Lightning to even the Stanley Cup Finals at two games apiece.
Corey Crawford provided a solid performance in net, making 24 saves to lift Chicago to a 2-1 victory over Tampa Bay in Game 4 at United Center on Wednesday night.
Jonathan Toews scored his first goal of the series for the Blackhawks, who improved to 4-0 in Game 4s and 8-2 at home this postseason.
Alex Killorn provided the Lightning's lone marker and Andrei Vasilevskiy stopped 17 shots during a surprise playoff start, the first of his career, in place of an injured Ben Bishop.
All four games of the Finals have been decided by one goal.
The best-of-seven series will continue Saturday with Game 5 at Amalie Arena in Tampa Bay.