With it tied 3-3 in entering the eighth, Trout led off by blasting a pitch from Franciso Cordero (3-5) off the window of second-deck restaurant at Rogers Center for a go-ahead solo blast.
Two outs later, Trumbo added a two-run shot for the Angels, who tacked on four more runs in the ninth to gain a split in their four-game road series.
Alberto Callaspo provided a two-run homer and Albert Pujols chipped in an RBI for the victors.
Jason Isringhausen (3-0) was credited with the win thanks to a scoreless seventh inning.
Colby Rasmus knocked a three-run homer and J.P. Arencibia added a solo shot for Toronto.