After spotting the Royals an early 3-0 lead, the Tribe roared back with six runs in the third. Shin-Soo Choo provided an two-run double and Jack Hannahan added a run-scoring single in the big frame.
Ubaldo Jimenez (1-0) earned the victory despite allowing nine hits over five innings. He yielded four runs, walked three and struck out five.
Royals starter Luis Mendoza (0-2) was shelled for nine runs (five earned) on nine hits before coming out after four full innings.