GLENDALE, Ariz., Sept. 27 (UPI) -- Peyton Manning connected for four touchdown passes and 379 yards passing Sunday in the Indianapolis Colts' 31-10 thrashing of Arizona.
Manning went 24-of-35 passing and threw TD passes to four different receivers as the Colts amassed 505 yards total offense.
Reggie Wayne caught seven passes for 126 yards and a TD and tight end Dallas Clark had seven catches for 62 yards and a score. Pierre Garcon caught a 53-yard scoring strike and Joseph Addai gained 63 yards rushing and caught a 3-yard TD pass for the Colts (3-0), who won their 12th consecutive regular-season game -- the longest current streak in the NFL.
The Indianapolis defense sacked Cardinals quarterback Kurt Warner three times, forced two fumbles and came up with two interceptions.
Warner was 30-of-52 passing for 332 yards and a 10-yard touchdown pass to Anquan Boldin, who finished with six catches for 83 yards. Steve Breaston caught seven passes for 94 yards and Larry Fitzgerald picked up 76 yards on seven catches for Arizona (1-2), which gained just 24 yards on the ground.