Both players are listed as probable.
But Tennessee starting center Kevin Mawae will not play because of an elbow injury -- though his status was the subject of much debate earlier this week. Mawae ruled himself out before coach Jeff Fisher said he was day-to-day.
That means second-year lineman Leroy Harris is likely to start under center for the Titans in place of the 13-year veteran Mawae. Harris also started in Tennessee's regular-season finale against Indianapolis.
Haynesworth suffered a sprained medial collateral ligament of the knee in Week 15 against Houston, but the team already had clinched the AFC South and a first-round bye in the NFL playoffs.
Seven-year veteran Vanden Bosch has struggled with a groin injury throughout this season and played in just 10 games.
Also out for Tennessee are backup defensive end Dave Ball with a back injury and safety Tuff Harris with a calf injury.