Fred Taylor and Maurice Jones-Drew combined for 116 yards for the Jaguars. Taylor scored one TD on 21 carries.
David Garrard piled up most of his passing stats late in the contest, completing 25-of-35 attempts for 287 yards with one touchdown and an interception.
Matt Jones caught eight passes for 104 yards for Jacksonville (4-8).
The Texans scored on a 69-yard drive on their first possession and controlled the tempo of the game from there. They went up 13-0 before Jacksonville scored on a third-quarter field goal but that's all the points the Jaguars could must in the first 57 minutes of the game.