The Sonics, who had six players in double figures, out-scored the Timberwolves 36-16 in the second period and 27-13 in the third. However, Seattle lost two key players -- first-round draft pick Kevin Durant and starting forward Chris Wilcox -- to injuries.
The game was 11 minutes old when Durant went out with a sprained left index finger. Wilcox had 14 points and 11 rebounds when he came out in the third quarter with a sprained left knee.
Al Jefferson had 17 points and eight rebounds for the Timberwolves, who have lost four straight and 10 out of their last 11.