The Wolverines (11-0, 7-0 Big Ten) will travel to Columbus next Saturday for a showdown with top-ranked Ohio State. The Buckeyes also remained unbeaten with a 54-10 victory over Northwestern.
Henne completed 11-of-15 passes with an interception. Hart rushed for 92 yards on 19 carries in the win. Steve Breaston caught three passes for 103 yards and a touchdown and returned a punt 83 yards for another TD.
Indiana (5-6, 3-4) has lost three of its last four games. Kellen Lewis completed 16-of-33 passes for the losers.