The Brewers have won four in a row. Torii Hunter belted two home runs and Shannon Stewart had one for the Twins.
Ace Minnesota southpaw Johan Santana fell to 7-4. Despite his seven strikeouts, Santana was pelted for six runs on six hits in five innings with four walks.
The winner was reliever Matt Wise, who improved to 1-2. Derrick Turnbow earned his 14th save.
Carlos Lee added a double and two RBI for Milwaukee. Minnesota has dropped six of seven and 10 of 15 overall.