Lewis was AFC Offensive Player of the Week. Favre was his NFC counterpart.
Lewis had 205 rushing yards and two touchdowns in the Ravens' 35-0 rout of Cleveland. It was his second huge game this year against the Browns.
In Week 3, he gained 295 yards.
Favre, playing with a heavy heart after the tragic death of his father on Sunday, went 22-of-30 for 399 yards and four touchdowns Monday night as the Packers buried Oakland, 41-7.
He had a career-best single game passes rating of 154.9 and moved into second place all-time for touchdown passes behind Hall of Famer Fran Tarkenton.
Also honored in the AFC were linebacker Willie McGinest of New England (defense) and punter Craig Hentrich of Tennessee (special teams). They were joined in the NFC by defensive back Tony Parrish of San Francisco (defense) and Dallas placekicker Billy Cundiff (special teams).