With temperatures reaching 106 degrees in the fourth quarter, Favre tried to rally the Packers (1-2). He moved them 68 yards to the Arizona seven-yard line in the final minute, then threw two incompletions in the end zone.
On third and goal, Jackson stepped in front of a pass intended for tight end Bubba Franks and returned it to his own 15.
The Cardinals (1-2) took the lead with 4:59 remaining on a one-yard toss from Jeff Blake to fullback James Hodgins. That capped a 68-yard drive that started with a 28-yard pass interference penalty on cornerback Al Harris.