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Brain memory 'booster' identified

IRVINE, Calif., Dec. 14 (UPI) -- U.S. researchers say they've identified a protein that boosts memory, a finding that could be benefit people with cognitive disorders.

Researchers at the University of California, in collaboration with scientists at Germany's University of Munster, found that a small protein called neuropeptide S can strengthen and prolong memories of everything from negative events to simple objects, a UC Irvine release said Tuesday.

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The discovery could provide important clues about how the brain stores memories and also lead to new treatments for Alzheimer's disease, dementia and other cognitive impairments, Rainer Reinscheid, a UC Irvine associate professor of pharmaceutical sciences, said.

"Additionally, it may help us better understand post-traumatic stress disorder, which involves exaggerated memories of traumatic events," he said.

In tests on mice, the researchers found that if neuropeptide S receptors in the brain were activated immediately after a learning experience, it could be recalled for much longer and with much greater intensity.

This memory enhancement lasted up to a week, Reinscheid said.

If, on the other hand, NPS receptor activation was disrupted, the mice didn't remember events as strongly, or sometime even at all, when tested just a day or two later.

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