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Study: Monkey malaria widespread in humans

SARAWAK, Malaysia, Jan. 17 (UPI) -- A Malaysian study suggests a potentially fatal species of malaria found in monkeys is being commonly misdiagnosed as a more benign form of the disease.

Researchers studied more than 1,000 samples from malaria patients using DNA-based technology and found more than one in four patients infected with Plasmodium knowlesi, a malaria parasite of macaque monkeys. But those infections were most often misdiagnosed as the normally uncomplicated human malaria caused by P. malariae.

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Until recently, P. knowlesi, was thought to infect only monkeys. But the new study, published in the journal Clinical Infectious Diseases by Professors Janet Cox-Singh and Balbir Singh of University Malaysia Sarawak, showed P. knowlesi malaria is widespread in Malaysia.

"Given the evident severity of the illness that it causes, I would recommend that doctors treating patients with a laboratory diagnosis of P. malariae remain alert to the possibility that they may be dealing with the potentially more aggressive P. knowlesi," said Cox-Singh. "This would be particularly important in patients who have spent time in the forest fringe areas of Southeast Asia where the non-human primate host exists."

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The research is reported in the journal Clinical Infectious Diseases.

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