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The day became an annual event marked on the third Thursday in April and the originators incorporated a charity in 2011 to use the annual holiday to raise money for various causes.
National High Five Day 2022 is dedicated to raising money for CoachArt, a nonprofit that works to give arts and sports experiences to children with chronic illnesses.
Other holidays and observances for April 21 include International Pizza Cake Day, Bulldogs are Beautiful Day, Big Word Day, National Chocolate Covered Cashews Truffle Day, National Tea Day and National Yellow Bat Day.