The bubble has 36 buoyancy balls on each side and Baluchi will be equipped with a life vest containing a water filter, a GPS tracking device, and shark repellent.
Baluchi attempted the trip once before in October 2014, but his voyage was cut short when Coast Guard officials rescued him after his GPS fell into the ocean 70 miles off of St. Augustine.
"They burst my bubble, and now I put signs up that say 'Please don't burst my bubble,'" he said.
Baluchi is an endurance athlete and has also attempted other feats including surviving six weeks in Death valley and running around the perimeter of the United States.
He also said he began jumping rope in a sauna and running 20 miles a day to prepare for the trip.
Baluchi said that he uses his stunts to raise money for children in need and plans to run through every country in the world to gather funds for that cause.
"I try to do the best thing from my heart. Giving help to children," he said.
He began his journey by casting off from Pompano Beach on Wednesday afternoon and requested that Coast Guard officials leave him alone this time around.