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Blood test may reduce antibiotic use for COPD patients

By Tauren Dyson

July 11 (UPI) -- A blood test may cut back on needless antibiotic prescriptions for patients with chronic obstructive pulmonary disease a new study says.

The number of COPD patients who received antibiotics prescriptions fell by 20 percent after taking the finger-prick blood test to measure their C-reactive protein levels, according to research published Thursday in New England Journal of Medicine.

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More than 11 million people in the United States are living with COPD, according to the American Lung Association.

"This is a patient population that is often considered to be at high risk from not receiving antibiotics, but we were able to achieve a reduction in antibiotic use that is about twice the magnitude of that achieved by most other antimicrobial stewardship interventions, and demonstrate that this approach was safe," Nick Francis, a researcher from the Cardiff University School of Medicine and study author, said in a news release.

The level of C-reactive protein in the blood is an indication of the inflammation in the blood caused by a serious infection. Antibiotics don't do much to help people having a COPD flare-up with low C-reactive protein levels, the researchers say.

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Overprescribing of antibiotics can lead to resistance of the drug, killing 23,000 people in the United States annually, according to the Centers for Disease Control and Prevention.

"This is a really important study which provides clear evidence that a simple biomarker blood test carried out in general practitioner surgeries on people with chronic obstructive pulmonary disease experiencing flare-ups, has the potential to reduce unnecessary prescribing of antibiotics, without adversely affecting recovery from these flare-ups. This, in turn, helps tackle the wider global health hazards of antimicrobial resistance," said Hywel Williams, a researcher at the National Institute for Health Research.

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