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Vitamin D linked to lower miscarriage risk

By HealthDay News

SATURDAY, June 2, 2018 -- Women who've had a miscarriage are more likely to get pregnant and have a baby if they have adequate levels of vitamin D, new research indicates.

"Our findings suggest that vitamin D may play a protective role in pregnancy," said lead investigator Sunni Mumford, from the epidemiology branch of the U.S. National Institute of Child Health and Human Development.

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Previous studies have shown that in vitro fertilization is more successful among women with higher levels of vitamin D, the study authors explained in a news release from the U.S. National Institutes of Health.

But the investigators noted there is little evidence on the link between vitamin D and pregnancy rates/pregnancy loss among women not using reproductive technologies.

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For the study, the researchers examined the vitamin D levels of 1,200 women with a history of miscarriage before they got pregnant again. Their vitamin D levels were also tested when they were eight weeks' pregnant.

Although it doesn't prove cause and effect, the study showed that the women who had sufficient vitamin D levels, or concentrations of 30 nanograms per milliliter (ng/mL) or more, were 10 percent more likely to become pregnant and 15 percent more likely to have a live birth than those with lower levels of vitamin D.

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Among the women who got pregnant, every 10 ng/mL increase in vitamin D before conception was associated with a 12 percent lower risk of miscarriage. The researchers reported that by the eighth week of pregnancy, vitamin D levels were no longer linked to pregnancy loss.

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The findings were published May 30 in The Lancet Diabetes & Endocrinology.

The study authors noted that more research is needed to determine if vitamin D supplements could reduce the risk of pregnancy loss among women at high risk for miscarriage.

More information

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The Harvard School of Public Health has more about vitamin D.

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