PHILADELPHIA, Nov. 8 (UPI) -- Genistein, a natural chemical found in soy, may prevent the spread of prostate cancer, researchers at Northwestern University in Chicago say.
Dr. Raymond Bergan, director of experimental therapeutics at the Lurie Cancer Center, says so far the cancer therapy drug has worked in preclinical animal studies and shows promise in humans with prostate cancer.
A recent phase II randomized study of 38 men with localized prostate cancer found genistein, given one month prior to surgery, had beneficial effects on prostate cancer cells, Bergan says.
Another phase II trial will see if the non-toxic drug can stop the cancer cells from moving out of the prostate and spreading.
"All therapies designed to stop cancer cell movement that have been tested to date in humans have basically failed have because they have been ineffective or toxic," Bergan says in a statement. "If this drug can effectively stop prostate cancer from moving in the body, theoretically, a similar therapy could have the same effect on the cells of other cancers."
These findings are scheduled to be presented at the Ninth Annual American Association for Cancer Research Frontiers in Cancer Prevention Research Conference in Philadelphia.