Differences between Crohn's and colitis

Feb. 9, 2010 at 12:07 AM
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SWANSEA, Wales, Feb. 9 (UPI) -- British researchers said they found distinct demographic profiles for Crohn's disease and colitis -- inflammatory bowel diseases.

Researchers at the School of Medicine, Swansea University and the University of Oxford analyzed data for 3,000 patients hospitalized in Wales from 1999-2007. They found several demographic differences between patients with severe Crohn's disease -- inflammation deep into tissues anywhere in the digestive track -- and patients with ulcerative colitis, inflammation including ulcers in stretches of the lining of the large intestine and rectum.

The study, published in the World Journal of Gastroenterology, found the prevalence of Crohn's disease was higher in females, 57.4 percent, than in males, 42.2 percent, and was highest in people ages 16-29. However, the prevalence of ulcerative colitis was similar in females and males -- about 50.1 percent -- and increased continuously with age.

Mortality was 6.8 percent and 14.6 percent after one and five years follow-up for Crohn's disease, and 9.2 percent and 20.8 percent after one and five years for ulcerative colitis.

"The hospitalized prevalence of severe Crohn's disease was slightly higher among the most deprived groups but there was no association between social deprivation and severe ulcerative colitis," the study authors said in a statement.

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