CALGARY, Alberta, Aug. 27 (UPI) -- PDE5 inhibitor Levitra was found more effective when used on demand for erectile dysfunction in men following prostate removal, Canadian researchers say.
The study involved 87 centers across Europe, the United States, Canada and South Africa between December 2004 and September 2007.
A total of 423 patients completed the study. The inclusion of the on-demand dosing regimen enabled comparison of the currently recommended guidelines for the use of PDE5 inhibitors with a proposed nightly dosing regimen. The results clearly show that nightly dosing with vardenafil does not have any effect beyond that of on-demand use.
The study, published in European Urology, shows that on-demand use of vardenafil during the treatment period was associated with significantly greater erectile function and sexual intercourse completion rates compared to placebo. The success rates for the vardenafil on-demand group were also higher than for the nightly group.