Hiddleston introduced the clip on Sunday during the 2021 MTV Movie & TV Awards.
Hiddleston's Loki meets Owen Wilson's Agent Mobius inside of an elevator as the God of Mischief is taken into custody by the Time Variance Authority.
"I'm taking you someplace to talk," Mobius says. "Well, I don't like to talk," Loki replies.
"But you do like to lie, which you just did because we both know you love to talk," Mobius says.
Loki is being held by the TVA after taking the Tesseract in 2019's Avengers: Endgame. The organization protects the proper flow of time, which has been messed up by Loki taking the Tesseract.
Loki remarks on how the TVA was created by the Time-Keepers and refers to them as space lizards as the footage ends.
Gugu Mbatha-Raw, Sophia Di Martino, Wummi Mosaku and Richard E. Grant also star in Loki, which is coming to Disney+ on June 9.
Kate Herron serves as director with Michael Waldron as head writer.
Marvel won multiple awards at the MTV Movie and TV Awards including Best Show for WandaVision.