Dick Clark Productions announced Wednesday that Biden, the president-elect, and Jill Biden will appear during the TV special Thursday.
Biden and Jill Biden will share "a special message of hope, unity, and best wishes for the year ahead," producers said in a statement.
"In a year marked with many challenges, we are honored that President-Elect Joe Biden and Dr. Biden will join America's most-watched tradition -- Dick Clark's New Year's Rockin' Eve -- to share an inspiring message as we come together to close out 2020 and look ahead with hope to 2021," producers added.
"We will have our heroes of 2020 -- we'll have the first responders, the essential workers. Many of them don't call themselves heroes, but we'll have a chance to meet them, meet their families, and celebrate what they have done for us this year," Seacrest said.
New Year's Rockin' Eve will begin airing Thursday at 8 p.m. EST on ABC. Other New Year's Eve specials include NBC's New Year's Eve, featuring Gwen Stefani and Kylie Minogue, and a performance by Gloria Gaynor.