Carrey played Biden in several episodes this season when the former U.S. senator and vice president was campaigning for the presidency.
Now that Biden is president-elect and expected to be inaugurated next month, Carrey has bowed out of future impressions of him.
"Though my term was only meant to be 6 weeks, I was thrilled to be elected as your SNL President ... comedy's highest call of duty. I would love to go forward knowing that Biden was the victor because I nailed that (expletive.) But I am just one in a long line of proud, fighting SNL Bidens!" Carrey tweeted Saturday.
No replacement for Carrey has been announced. A new episode of the sketch-comedy show airs this weekend.