Doogie Kameāloha, M.D. is expected to follow Lahela "Doogie" Kameāloha, a mixed race 16-year-old doctor in Hawaii.
An actress has not been announced for the titular character.How I Met Your Mother and Fresh Off the Boat alum Kourtney Kang is writing and executive producing the project.
"Thirty years ago, a young medical prodigy took the world by storm and left a lasting impact on pop culture," Ricky Strauss, president of content and marketing at Disney+, said in a statement.
"Kourtney and the team at 20th Television have created a very modern take on this beloved property which will resonate with our global Disney+ audience. We can't wait to introduce the world to the new Doogie!"
The original ran for four seasons 1989-93. It also was about a brilliant teen physician.