"A drama series by #GillianFlynn starring @JohnCusack is an actual utopia, so this works," the streaming service tweeted Tuesday.
Variety said Gone Girl scribe Flynn will serve as showrunner for Utopia.
The Hollywood Reporter said the series is about a group of young people hunted by a mysterious organization after they discover an underground comic book filled with conspiracy theories.
Cusack, 52, will play a philanthropic, tech genius on the show.
The actor is known for his work in the films Better Off Dead, Say Anything, Grosse Pointe Blank, Midnight in the Garden of Good and Evil, High Fidelity, Being John Malkovich and America's Sweethearts. Utopia marks his first series regular role.