The Righteous Gemstones will follow Goodman as Eli, the patriarch of the Gemstone family, whose time as a world-famous Christian minister with a weekly television program is fading. McBride will portray Eli's eldest son, who is modernizing his father's empire.
The Gemstone family is described as having a long history of deviance, greed and charitable work, all done in the name of Jesus Christ.
McBride, who will direct the pilot episode, is also serving as a writer and executive producer on the comedy along with Jody Hill and David Gordon Green.
McBride, Hill and Green previously worked on HBO comedy series Vice Principals and Eastbound & Down. The trio also collaborated on the Netflix film The Legacy of a Whitetail Deer Hunter, which arrives on the streaming service on July 6.